Protective effect of Moringa olifera Leaves Extracts and silymarin on hepatic Toxicity Induced by Cyclophosphamide.
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منابع مشابه
Protective Effect of Moringa Peregrina Leaves Extract on Acetaminophen -induced Liver Toxicity in Albino Rats
BACKGROUND Acetaminophen is a common antipyretic drug but at overdose can cause severe hepatotoxicity that may further develop into liver failure and hepatic centrilobular necrosis in experimental animals and humans. This study was undertaken to assess the ameliorative role of Moringa peregrina leaves extract against acetaminophen toxicity in rats. MATERIALS AND METHODS Induction of hepatotox...
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Cyclophosphamide (CP) is a drug commonly used to treat neoplastic disease and some autoimmune diseases. It is also a well-known and well-studied teratogen causing a variety of birth defects in fetuses of pregnant women treated with the drug. There are many reports that show the adverse effects of CP can be decreased by use of antioxidant drugs. It appears that, quercetin has antioxidant effect....
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Background and Aims: Lipopolysaccharide (LPS) triggers production of reactive oxygen species and inflammatory cytokines. Nowadays Silybum marianum has been shown to treat liver and gall bladder disorders, especially to protect the liver against poisoning from various toxins. Therefore, we decided to evaluate the protective effect of silymarin on LPS-induced liver toxicity in male Wistar rat. M...
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To evaluate the effect of ethanolic extract of leaves of Moringa olifera Lam. on acetic acid induced colitis in albino rats ethanolic extract of Moringa olifera was prepared by percolation method. Acute toxicity test was done by using OECD guidelines. Albino rats were divided into four groups (n=5). Group A and B received 3% gum acacia. Group C and D received ethanolic extract of Moringa olifer...
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BACKGROUND ALL is the most common childhood malignancy. The children with ALL are treated with methotrexate (MTX) based chemotherapy protocols. MTX causes unpredictable serious hepatic and renal side effects. Silymarin has antioxidant and anti-inflammatory activities and stimulates tissue regeneration. This study aims to evaluate the protective effects of Silymarin on MTX-based chemotherapy-ind...
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ژورنال
عنوان ژورنال: Arab Universities Journal of Agricultural Sciences
سال: 2019
ISSN: 2636-3585
DOI: 10.21608/ajs.2019.17109.1090